
NEW ! High Power LEDs Now available.
Red Light Therapy LEDS, along with infrared
and other colors.
Check back often as I add more products.
Some Background Information
“Low-energy photon irradiation by light in the far-red to near-IR spectral range
with low-energy lasers or LED arrays has been found to modulate various
biological processes in cell culture and animal models. This phenomenon of
photobiomodulation has been applied clinically in the treatment of soft tissue
injuries and the acceleration of wound healing. The mechanism of
photobiomodulation by red to near-IR light at the cellular level has been
ascribed to the activation of mitochondrial respiratory chain components,
resulting in initiation of a signaling cascade that promotes cellular
proliferation and cytoprotection.”
“A growing body of evidence suggests that cytochrome oxidase is a key
photoacceptor of light in the far-red to near-IR spectral range." Dr. Harry
Whelan (NASA)
"Cytochrome oxidase is an integral membrane protein that contains four redox
active metal centers and has a strong absorbance in the far-red to near-IR
spectral range detectable in vivo by near-IR spectroscopy.”
“Moreover, 660–680 nm of irradiation has been shown to increase electron
transfer in purified cytochrome oxidase, increase mitochondrial respiration and
ATP synthesis in isolated mitochondria, and up-regulate cytochrome oxidase
activity in cultured neuronal cells.”
“LED photostimulation induces a cascade of signaling events initiated by the
initial absorption of light by cytochrome oxidase. These signaling events may
include the activation of immediate early genes, transcription factors,
cytochrome oxidase subunit gene expression, and a host of other enzymes and
pathways related to increased oxidative metabolism.”
“In addition to increased oxidative metabolism, red to near-IR light stimulation
of mitochondrial electron transfer is known to increase the generation of
reactive oxygen species. These mitochondrially generated reactive oxygen species
may function as signaling molecules to provide communication between
mitochondria and the cytosol and nucleus.”